Causes of Cirrhosis
Cirrhosis may be the result of many conditions. In the United States, chronic alcoholism and hepatitis C are the most common culprits.
Alcoholic Liver Disease: Chronic, long-term alcoholism is the first thing most people think of when they hear cirrhosis of the liver. It takes a long time to develop, usually after a decade or more of heavy drinking. However, the amount of alcohol that causes this condition can vary greatly from person to person. The liver becomes damaged when alcohol blocks the normal breakdown of protein, fats, and carbohydrates, or so most doctors postulate.
Chronic Hepatitis (B, C, and D): Hepatitis is probably the leading cause of cirrhosis of the liver worldwide. In the United States, hepatitis C and alcoholic liver disease are the top two causes. hepatitis B and hepatitis D are less common in the U.S., although they have the same effect as hepatitis C. Viral infection of the liver causes inflammation and low grade damage over the long term, eventually resulting in cirrhosis. Hepatitis D only affects those who already have hepatitis B.
Autoimmune Hepatitis: When your immune system attacks your own liver, it can lead to inflammation, damage, scarring, and cirrhosis.
Nonalcoholic Steatohepatitis (NASH): This is a form of hepatitis that appears to accompany diabetes, protein malnutrition, obesity, coronary artery disease, and treatment with corticosteroid medications.It causes fat buildup in the liver and, eventually,the formation of scar tissue.
Inherited Diseases: Alpha-1 antitrypsin deficiency, hemochromatosis, Wilson’s disease, galactosemia, and glycogen storage diseases are inherited conditions that can cause cirrhosis. They interfere with the way the liver produces, processes, and stores proteins, enzymes, metals, and other substances that are essential to proper bodily function.
Blocked Bile Ducts: Damage to the bile ducts can cause them to become blocked. When bile backs up in the liver, it begins to damage the surrounding tissue. It is often a congenital defect found in infants. In adults, the bile ducts usually become blocked as a result of secondary biliary cirrhosis. In patients who undergo gallbladder surgery, this condition is sometimes caused by inadvertent damage to the ducts during surgery.
Drugs, Toxins, and Infections: Prescription drugs, the parasitic infection schistosomiasis,environmental toxins, and repeated bouts of heart failure with liver congestion can all lead to cirrhosis.
If you are currently suffering from any of these conditions, contact us to schedule a consultation with Dr. Tabib today.